Separation of sublethal and lethal effects of polymorphonuclear leukocytes on Escherichia coli.

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Separation of sublethal and lethal effects of polymorphonuclear leukocytes on Escherichia coli.

Escherichia coli ingested by PMN promptly stop growing and form no colonies in nutrient agar, but metabolize near normally for up to several hours. The bactericidal/permeability increasing protein (BPI) of PMN also inhibits E. coli growth without initial metabolic impairment. We recently showed that BPI-treated E. coli, although unable to grow in normal nutrient agar, can form colonies in this ...

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Escherichia coli ingested by PMN promptly stop growing and form no colonies in nutrient agar, but metabolize near normally for up to several hours. The bactericidal/permeability increasing protein (BPI) ofPMN also inhibits E. coli growth without initial metabolic impairment. We recently showed that BPItreated E. coli, although unable to grow in normal nutrient agar, can form colonies in this me...

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ژورنال

عنوان ژورنال: Journal of Clinical Investigation

سال: 1990

ISSN: 0021-9738

DOI: 10.1172/jci114755